PISSTON PROSTATE HERBAL HEALTH - ALL NATURAL SUPPLEMENTS
Referenced from: "NCCIH.NIH.GOV Clinical Digest for health professionals"
A 2014 randomized trial of 225 men with lower urinary tract symptoms and BPH examined the efficacy and tolerability of combination therapy between saw palmetto, lycopene, and selenium plus tamsulosin versus single therapies. The findings suggest that a combination therapy of saw palmetto, lycopene, selenium, and tamsulosin is more effective than single therapies in improving International Prostate Symptom Score and increasing maximum urinary flow rate. It was noted that after 6 months of treatment, the combination therapy significantly improved symptom scores compared with single therapy, and from 6 to 12 months, combination therapy demonstrated significant improvement in urine flow rate compared to tamsulosin alone. There were no reported treatment-related adverse events associated with combination therapy.
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A 2018 phase IV, non-inferiority, open-label, clinical trial (SPRITE study) of 404 participants found that treatment with saw palmetto, selenium, plus lycopene (SeR-Se-Ly) was not inferior to tadalafil 5 mg for improving the International Prostate Symptom Score and maximum urinary flow rate in men with lower urinary tract symptoms.
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